Abstract:
High meat-product consumption has been
related to cardiovascular disease (CVD). However, pre vious results suggest the benefits of consuming im proved fat meat products on lipoprotein-cholesterol
and anthropometric measurements. Present study aims
to assess the effect of consuming different Pâté and
Frankfurter formulations on emergent CVD biomarkers
in male volunteers at increased CVD risk. Eighteen male
volunteers with at least two CVD risk factors were
enrolled in a sequentially controlled study where differ ent pork-products were tested: reduced-fat (RF), omega 3-enriched-RF (n-3RF), and normal-fat (NF). Pork products were consumed during 4-week periods sepa rated by 4-week washout. The cardiometabolic index
(CI), oxidized low density lipoproteins (oxLDL), apoli poproteins (Apo) A1 and B, homocysteine (tHcys),
arylesterase (AE), C-reactive Protein (CRP), tumor ne crotic factor-alpha (TNF¿), and lipoprotein (a) (Lp(a))
were tested and some other related ratios calculated. AE,
oxLDL and Lp(a), AE/HDLc, LDLc/Apo B, and AE/
oxLDL rate of change were differently affected
(P<0.01) by pork-products consumption. RF increased
(P < 0.05) AE, AE/HDLc and AE/oxLDL ratios and
decreased TNF¿, tHcys; n-3RF increased (P < 0.001)
AE, AE/HDLc and AE/oxLDL ratios and decreased
(P < 0.05) Lp(a); while NF increased (P<0.05) oxLDL
and Lp(a) levels. In conclusion, RF and n-3RF products
affected positively the level of some emergent CVD
markers. The high regular consumption of NF products should be limited as significantly increased
Lp(a) and oxLDL values. The high variability in re sponse observed for some markers suggests the need
to perform more studies to identify targets for RF- and n 3RF-products
