APA
Algar, Juan & Docampo Vázquez, Cristian & Rico Romano, Cristina & Boquete Castro, Ana & Obispo Díaz, Cristina & Aragoneses, Juan Manuel (2025-04-02 ) .Randomised Clinical Trial: Effect of AH Plus and Neosealer Flo on Postoperative Pain and Healing of Periapical Lesions.
ISO 690
Algar, Juan & Docampo Vázquez, Cristian & Rico Romano, Cristina & Boquete Castro, Ana & Obispo Díaz, Cristina & Aragoneses, Juan Manuel. 2025-04-02 .Randomised Clinical Trial: Effect of AH Plus and Neosealer Flo on Postoperative Pain and Healing of Periapical Lesions.
https://hdl.handle.net/20.500.12080/45632
Abstract:
Apical periodontitis is a common inflammatory condition associated with root
canal treatment (RCT) failure. The quality of the three-dimensional root canal seal is critical
to the success of the treatment. Bioceramic sealants, such as Neosealer Flo, offer biological
advantages such as osteoconduction, biocompatibility and sustained calcium ion release,
which may improve apical healing. The aim of this study was to compare AH Plus and
Neosealer Flo in terms of postoperative pain, extrusion and periapical healing. A single blind, randomised clinical trial was conducted with 60 patients divided into AH Plus and
Neosealer Flo groups. Post-operative pain was assessed using a visual analogue scale
(VAS) at 24 and 48 h and at 7 days. Seal quality and periapical healing were assessed at 6
months using the AAE success criteria by clinical and radiographic evaluation. Neosealer
Flo resulted in less postoperative pain at 24 h and 7 days compared to AH Plus. Extrusion
did not significantly affect pain or correlate with the type of sealer used. Both materials
achieved similar periapical healing rates. Neosealer Flo demonstrated advantages in pain
reduction, while both sealants showed comparable efficacy.