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Stem Cell Therapy for Digestive Tract Diseases: Current State and Future Perspectives

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APA

Trebol Lopez, Jacobo & Georgiev Hristov, Tihomir & García Arranz, Mariano & García Olmo, Damián (2010-12 ) .Stem Cell Therapy for Digestive Tract Diseases: Current State and Future Perspectives.

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Trebol Lopez, Jacobo & Georgiev Hristov, Tihomir & García Arranz, Mariano & García Olmo, Damián. 2010-12 .Stem Cell Therapy for Digestive Tract Diseases: Current State and Future Perspectives.

https://hdl.handle.net/20.500.12080/39638
dc.contributor.author Trebol Lopez, Jacobo
dc.contributor.author Georgiev Hristov, Tihomir
dc.contributor.author García Arranz, Mariano
dc.contributor.author García Olmo, Damián
dc.date.accessioned 2024-02-09T10:42:34Z
dc.date.available 2024-02-09T10:42:34Z
dc.date.created 2010-12
dc.date.issued 2010-12
dc.identifier.uri https://hdl.handle.net/20.500.12080/39638
dc.description.abstract Diseases of the digestive tract are complex and encompass a broad spectrum of different pathogeneses (inflammatory, ischemic, neoplastic, and functional deficit). The digestive tract is not a sterile environment, and its organs are composed of tissues with different embryologic origin and different morphologic and functional complexity. As a consequence, the management of these diseases is often challenging. Stem cell (SC) therapy has yielded some promising results in preclinical studies, and, recently, some approaches have been tested clinically. Indeed, during the last 5 years, the number of clinical trials with SCs for treatment of digestive tract diseases has increased 10-fold. The most advanced programs involve liver failure, Crohn's disease, and fistulous disease and are now in phase III of development. If progress continues and the preliminary results are confirmed, SC therapy will become a clinical reality in the near future. In this review we examine the basic concepts of the SC therapy, analyze the potential benefits of SCs in diseases of the digestive tract, and summarize current experience in the field and the future perspectives. es_ES
dc.format application/acad es_ES
dc.language eng es_ES
dc.rights CC-BY es_ES
dc.rights.uri http://creativecommons.org/licenses/by/4.0/deed.es es_ES
dc.title Stem Cell Therapy for Digestive Tract Diseases: Current State and Future Perspectives es_ES
dc.type info:eu-repo/semantics/article es_ES
dc.rights.accessrights info:eu-repo/semantics/restrictedAccess es_ES
dc.identifier.location N/A es_ES


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