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Radiogenomics: Hunting Down Liver Metastasis in Colorectal Cancer Patients

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APA

de la Pinta, Carolina & Castillo, María Encarnación & Collado, Manuel & Galindo Pumariño, Cristina & Peña, Cristina (2021-11 ) .Radiogenomics: Hunting Down Liver Metastasis in Colorectal Cancer Patients.

ISO 690

de la Pinta, Carolina & Castillo, María Encarnación & Collado, Manuel & Galindo Pumariño, Cristina & Peña, Cristina. 2021-11 .Radiogenomics: Hunting Down Liver Metastasis in Colorectal Cancer Patients.

https://hdl.handle.net/20.500.12080/39552
dc.contributor.author de la Pinta, Carolina
dc.contributor.author Castillo, María Encarnación
dc.contributor.author Collado, Manuel
dc.contributor.author Galindo Pumariño, Cristina
dc.contributor.author Peña, Cristina
dc.date.accessioned 2024-02-07T14:39:14Z
dc.date.available 2024-02-07T14:39:14Z
dc.date.created 2021-11
dc.date.issued 2021-11
dc.identifier.uri https://hdl.handle.net/20.500.12080/39552
dc.description.abstract : Radiomics is a developing new discipline that analyzes conventional medical images to extract quantifiable data that can be mined for new biomarkers that show the biology of pathological processes at microscopic levels. These data can be converted into image-based signatures to improve diagnostic, prognostic and predictive accuracy in cancer patients. The combination of radiomics and molecular data, called radiogenomics, has clear implications for cancer patients¿ management. Though some studies have focused on radiogenomics signatures in hepatocellular carcinoma patients, only a few have examined colorectal cancer metastatic lesions in the liver. Moreover, the need to differentiate between liver lesions is fundamental for accurate diagnosis and treatment. In this review, we summarize the knowledge gained from radiomics and radiogenomics studies in hepatic metastatic colorectal cancer patients and their use in early diagnosis, response assessment and treatment decisions. We also investigate their value as possible prognostic biomarkers. In addition, the great potential of image mining to provide a comprehensive view of liver niche formation is examined thoroughly. Finally, new challenges and current limitations for the early detection of the liver premetastatic niche, based on radiomics and radiogenomics, are also discussed. Keywords: colon cancer; liver metastasis; radiogenomics; radiomics; metastatic niche; early detection es_ES
dc.format application/pdf es_ES
dc.language eng es_ES
dc.rights CC-BY es_ES
dc.rights.uri http://creativecommons.org/licenses/by/4.0/deed.es es_ES
dc.title Radiogenomics: Hunting Down Liver Metastasis in Colorectal Cancer Patients es_ES
dc.type info:eu-repo/semantics/article es_ES
dc.rights.accessrights info:eu-repo/semantics/openAccess es_ES
dc.identifier.location N/A es_ES


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