Répertoire de l'Université Alfonso X el Sabio

Immunocytochemical Light- and Electron-Microscopic Studies of Growth Hormone, Prolactin and Somatomammotroph Cells in Female Goat

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https://hdl.handle.net/20.500.12080/39449
dc.contributor.advisor Correas, Miguel Ángel
dc.contributor.author Vázquez, Fernando
dc.contributor.author Correas, Miguel Ángel
dc.contributor.author Serrano, Jose
dc.contributor.author Bernabé, Antonio
dc.date.accessioned 2024-02-01T07:22:15Z
dc.date.available 2024-02-01T07:22:15Z
dc.date.created 2002
dc.identifier.uri https://hdl.handle.net/20.500.12080/39449
dc.description.abstract We have studied the structural and ultrastructural changes that occur in growth hormone (GH), prolactin (PRL) and somatomammotroph (SMT) cells of female goats of the Murciano-Granadina breed during different physiological stages: prepuberty, anestrus, pregnancy and lactation. Serial sections were stained with double immunolabeling, alkaline phosphatase and avidin-biotin complex for light microscopy, and immunogold labeling was used for electron microscopy. These techniques allowed the identification of GH, PRL and SMT cells, which were evenly distributed throughout the whole pars distalis. PRL cells were the most frequent. Both PRL and GH cells showed morphological changes that may be related to a given physiological stage. These changes include the number of cells and the number and size of the secretory granules. SMT cells were clearly identified by having two types of monohormonal secretory granule showing single labeling, in spite of their similar ultrastructural characteristics to the other adenohypophysary cells. They are found in low percentages (0.6%). We postulate that cell aggregates which look like SMT syncytia may be artifacts caused by interdigitation of PRL and GH cells, and that cells which are normally taken to be SMT cells are not an interconversion stage between monohormonal cells. es_ES
dc.format other es_ES
dc.language eng es_ES
dc.rights Copyright es_ES
dc.rights.uri http://creativecommons.org/licenses/by/4.0/deed.es es_ES
dc.source Cells, tissues, organs es_ES
dc.subject Pituitary gland, Growth hormone cell, Prolactin cell, Somatomammotroph cell, Goat, female es_ES
dc.title Immunocytochemical Light- and Electron-Microscopic Studies of Growth Hormone, Prolactin and Somatomammotroph Cells in Female Goat es_ES
dc.type N/A es_ES
dc.rights.accessrights info:eu-repo/semantics/closedAccess es_ES
dc.accrualPolicy Publicación en curso es_ES
dc.identifier.location N/A es_ES


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