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Searching for the Optimal Donor for Allogenic Adipose-Derived Stem Cells: A Comprehensive Review

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Georgiev Hristov, Tihomir & García Arranz, Mariano & Trébol López, Jacobo & Barba Recreo, Paula & García Olmo, Damián .Searching for the Optimal Donor for Allogenic Adipose-Derived Stem Cells: A Comprehensive Review.

ISO 690

Georgiev Hristov, Tihomir & García Arranz, Mariano & Trébol López, Jacobo & Barba Recreo, Paula & García Olmo, Damián. Searching for the Optimal Donor for Allogenic Adipose-Derived Stem Cells: A Comprehensive Review.

https://hdl.handle.net/20.500.12080/39380
dc.contributor.author Georgiev Hristov, Tihomir
dc.contributor.author García Arranz, Mariano
dc.contributor.author Trébol López, Jacobo
dc.contributor.author Barba Recreo, Paula
dc.contributor.author García Olmo, Damián
dc.date.accessioned 2024-01-26T16:20:51Z
dc.date.available 2024-01-26T16:20:51Z
dc.date.created 2022-10
dc.identifier.uri https://hdl.handle.net/20.500.12080/39380
dc.description.abstract Adipose-derived stem cells comprise several clinically beneficial qualities that have been explored in basic research and have motivated several clinical studies with promising results. After being approved in the European Union, UK, Switzerland, Israel, and Japan, allogeneic adiposederived stem cells (darvadstrocel) have been recently granted a regenerative medicine advanced therapy (RMAT) designation by US FDA for complex perianal fistulas in adults with Crohn¿s disease. This huge scientific step is likely to impact the future spread of the indications of allogeneic adiposederived stem cell applications. The current knowledge on adipose stem cell harvest describes quantitative and qualitative differences that could be influenced by different donor conditions and donor sites. In this comprehensive review, we summarize the current knowledge on the topic and propose donor profiles that could provide the optimal initial quality of this living drug, as a starting point for further applications and studies in different pathological conditions. Keywords: adipose-derived stem cells; stem cell donor; allogenic stem cells es_ES
dc.format application/pdf es_ES
dc.language eng es_ES
dc.rights CC-BY es_ES
dc.rights.uri http://creativecommons.org/licenses/by/4.0/deed.es es_ES
dc.title Searching for the Optimal Donor for Allogenic Adipose-Derived Stem Cells: A Comprehensive Review es_ES
dc.type info:eu-repo/semantics/article es_ES
dc.rights.accessrights info:eu-repo/semantics/openAccess es_ES
dc.identifier.location N/A es_ES


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