Archivio dell'Università Alfonso X El Sabio

Elderly Population with COVID-19 and the Accuracy of Clinical Scales and D-Dimer for Pulmonary Embolism: The OCTA-COVID Study

Mostra i principali dati dell'item

APA

Quezada Feijoó, Dolores Maribel & Ramos Sánchez, Mónica & Lozano Montoya, Isabel & Sarró, Mónica & Cabo Muiños, Verónica & Ayala Muñoz, Rocío & Gómez Pavón, Francisco Javier & Toro, Rocío (2021-11 ) .Elderly Population with COVID-19 and the Accuracy of Clinical Scales and D-Dimer for Pulmonary Embolism: The OCTA-COVID Study.

ISO 690

Quezada Feijoó, Dolores Maribel & Ramos Sánchez, Mónica & Lozano Montoya, Isabel & Sarró, Mónica & Cabo Muiños, Verónica & Ayala Muñoz, Rocío & Gómez Pavón, Francisco Javier & Toro, Rocío. 2021-11 .Elderly Population with COVID-19 and the Accuracy of Clinical Scales and D-Dimer for Pulmonary Embolism: The OCTA-COVID Study.

https://hdl.handle.net/20.500.12080/26298
dc.contributor.author Quezada Feijoó, Dolores Maribel
dc.contributor.author Ramos Sánchez, Mónica
dc.contributor.author Lozano Montoya, Isabel
dc.contributor.author Sarró, Mónica
dc.contributor.author Cabo Muiños, Verónica
dc.contributor.author Ayala Muñoz, Rocío
dc.contributor.author Gómez Pavón, Francisco Javier
dc.contributor.author Toro, Rocío
dc.date.accessioned 2021-11-30T13:31:31Z
dc.date.available 2021-11-30T13:31:31Z
dc.date.created 2021-11-20
dc.date.issued 2021-11
dc.identifier.uri https://hdl.handle.net/20.500.12080/26298
dc.description.abstract Background: Elderly COVID-19 patients have a high risk of pulmonary embolism (PE), but factors that predict PE are unknown in this population. This study assessed the Wells and revised Geneva scoring systems as predictors of PE and their relationships with D-dimer (DD) in this population. Methods: This was a longitudinal, observational study that included patients ¿75 years old with COVID-19 and suspected PE. The performances of the Wells score, revised Geneva score and DD levels were assessed. The combinations of the DD level and the clinical scales were evaluated using positive rules for higher specificity. Results: Among 305 patients included in the OCTA-COVID study cohort, 50 had suspected PE based on computed tomography pulmonary arteriography (CTPA), and the prevalence was 5.6%. The frequencies of PE in the low-, intermediate- and high-probability categories were 5.9%, 88.2% and 5.9% for the Geneva model and 35.3%, 58.8% and 5.9% for the Wells model, respectively. The DD median was higher in the PE group (4.33 mg/L; interquartile range (IQR) 2.40¿7.17) than in the no PE group (1.39 mg/L; IQR 1.01¿2.75) (p < 0.001). The area under the curve (AUC) for DD was 0.789 (0.652¿0.927). After changing the cutoff point for DD to 4.33 mg/L, the specificity increased from 42.5% to 93.9%. Conclusions: The cutoff point DD > 4.33 mg/L has an increased specificity, which can discriminate false positives. The addition of the DD and the clinical probability scales increases the specificity and negative predictive value, which helps to avoid unnecessary invasive tests in this population. es_ES
dc.format application/pdf es_ES
dc.language eng es_ES
dc.rights CC-BY es_ES
dc.rights.uri http://creativecommons.org/licenses/by/4.0/deed.es es_ES
dc.subject pulmonary embolism; Wells scale; Geneva scale; COVID-19; older patients es_ES
dc.title Elderly Population with COVID-19 and the Accuracy of Clinical Scales and D-Dimer for Pulmonary Embolism: The OCTA-COVID Study es_ES
dc.type info:eu-repo/semantics/article es_ES
dc.rights.accessrights info:eu-repo/semantics/openAccess es_ES
dc.identifier.location N/A es_ES


Files in questo item

Questo item appare nelle seguenti collezioni

Mostra i principali dati dell'item

CC-BY Except where otherwise noted, this item's license is described as CC-BY

Cerca in DSpace


Ricerca

My Account

Social Media