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A Comparative Study of Biocompatibility in Rat Connective Tissue of a New Mineral Trioxide Compound (Theracal) versus MTA and a Bioactive G3 Glass

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APA

Mena Álvarez, Jesús & Rico Romano, Cristina & Gutiérrez Ortega, Carlos & Arias Sanz, Pablo & Castro Urda, Javier (2021-06 ) .A Comparative Study of Biocompatibility in Rat Connective Tissue of a New Mineral Trioxide Compound (Theracal) versus MTA and a Bioactive G3 Glass.

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Mena Álvarez, Jesús & Rico Romano, Cristina & Gutiérrez Ortega, Carlos & Arias Sanz, Pablo & Castro Urda, Javier. 2021-06 .A Comparative Study of Biocompatibility in Rat Connective Tissue of a New Mineral Trioxide Compound (Theracal) versus MTA and a Bioactive G3 Glass.

https://hdl.handle.net/20.500.12080/24550
dc.contributor.author Mena Álvarez, Jesús
dc.contributor.author Rico Romano, Cristina
dc.contributor.author Gutiérrez Ortega, Carlos
dc.contributor.author Arias Sanz, Pablo
dc.contributor.author Castro Urda, Javier
dc.date.accessioned 2021-06-28T15:27:17Z
dc.date.available 2021-06-28T15:27:17Z
dc.date.created 2021-06-08
dc.date.issued 2021-06
dc.identifier.uri https://hdl.handle.net/20.500.12080/24550
dc.description.abstract The aim of this paper was to assess the differences in tissue response to implantation during 15, 30 and 45 days in the subcutaneous connective tissue of Wistar rats from three biomaterials: Angelus MTA®, Theracal LC®, and Angelus MTA® to which 25% bioglass G3 was added. Twentyfour Wistar rats were used, the materials were inserted into the rat¿s dorsal area in silicone tubes 5 mm long by 1.5 mm diameter. Histological reaction was assessed at 15, 30, and 45 days after implantation. They were then stained with hematoxylin eosin and evaluated by two observers. Data were analyzed using Fisher¿s exact test and Mann¿Whitney¿s U test was used to determine the association between variables. Angelus MTA induced the formation of dystrophic calcifications twice as much as Theracal LC (p < 0.05). The addition of G3 did not affect the greater or lesser occurrence of calcifications (p > 0.05). Theracal LC and MTA plus G3 caused an inflammatory reaction, which was chronic at 15 days and decreased in intensity, almost disappearing after 45 days. Theracal LC, as well as Angelus MTA plus G3, were well tolerated when implanted in the subcutaneous connective tissue of rat. Histologically, no inconvenience was found for the use by direct contact of Theracal LC, and the mixture of MTA with 25% bioactive glass G3, in the tissue of Wistar rats. Keywords: mineral trioxide; G3 glass bioactive; Theracal; root-end sealers; endodontic surgery es_ES
dc.format application/pdf es_ES
dc.language eng es_ES
dc.rights CC-BY es_ES
dc.rights.uri http://creativecommons.org/licenses/by/4.0/deed.es es_ES
dc.title A Comparative Study of Biocompatibility in Rat Connective Tissue of a New Mineral Trioxide Compound (Theracal) versus MTA and a Bioactive G3 Glass es_ES
dc.type info:eu-repo/semantics/article es_ES
dc.description.curso 2020-2021 es_ES
dc.rights.accessrights info:eu-repo/semantics/openAccess es_ES
dc.identifier.location N/A es_ES


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