Repositorio Institucional de la Universidad Alfonso X el Sabio

Histomorphometric Comparison between Two Types of Acellular Dermal Matrix Grafts: A Mini Pig Animal Model Study

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APA

Aragoneses, Javier & Suárez, Ana & Rodríguez, Cinthia & Aragoneses, Juan Manuel .Histomorphometric Comparison between Two Types of Acellular Dermal Matrix Grafts: A Mini Pig Animal Model Study.

ISO 690

Aragoneses, Javier & Suárez, Ana & Rodríguez, Cinthia & Aragoneses, Juan Manuel. Histomorphometric Comparison between Two Types of Acellular Dermal Matrix Grafts: A Mini Pig Animal Model Study.

https://hdl.handle.net/20.500.12080/24525
dc.contributor.author Aragoneses, Javier
dc.contributor.author Suárez, Ana
dc.contributor.author Rodríguez, Cinthia
dc.contributor.author Aragoneses, Juan Manuel
dc.date.accessioned 2021-06-22T13:37:13Z
dc.date.available 2021-06-22T13:37:13Z
dc.date.created 2021-04-07
dc.identifier.uri https://hdl.handle.net/20.500.12080/24525
dc.description.abstract Acellular dermal matrix grafts (ADMG) have been used as soft tissue graft substitutes for autografts in periodontal plastic surgical procedures. They have benefits like avoiding a second surgical site and patient morbidity that have been associated with autografts, but there is limited evidence available on their tissue response and wound healing process. This histomorphometric animal model study was carried out in mini pigs and it aimed to compare the two types of ADMG materials of human and porcine derivative with a control group through observation of parameters like epithelial and Keratinized layer thickness, angiogenesis, cellularity, matrix resorption, and inflammatory infiltrate. The surgical technique involved punctures on the edentulous areas stripping the epithelial tissue and exposing the underlying connective tissue, placement of the ADMGs in the appropriate control and test sites. Following this, gingival biopsies were procured at three different time intervals of 15, 45, and 90 days. There were significant differences in epithelial and Keratinized layer thickness among the three groups. This study concluded that there was no clear consensus on which graft material was superior but it gave an insight into the tissue response and wound healing process associated with the graft materials. Keywords: animal model; acellular dermal matrix graft; angiogenesis; keratin; wound healing es_ES
dc.format application/pdf es_ES
dc.language eng es_ES
dc.rights CC-BY es_ES
dc.rights.uri N/A es_ES
dc.title Histomorphometric Comparison between Two Types of Acellular Dermal Matrix Grafts: A Mini Pig Animal Model Study es_ES
dc.type info:eu-repo/semantics/article es_ES
dc.rights.accessrights info:eu-repo/semantics/openAccess es_ES
dc.identifier.location N/A es_ES


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