APA
López Valverde, Nansi & López Valverde, Antonio & Aragoneses, Juan Manuel & Macedo de Sousa, Bruno & Rodrigues, María João & Ramírez, Juan Manuel .Systematic Review and Meta-Analysis of the Effectiveness of Calcium-Phosphate Coating on the Osseointegration of Titanium Implants.
ISO 690
López Valverde, Nansi & López Valverde, Antonio & Aragoneses, Juan Manuel & Macedo de Sousa, Bruno & Rodrigues, María João & Ramírez, Juan Manuel. Systematic Review and Meta-Analysis of the Effectiveness of Calcium-Phosphate Coating on the Osseointegration of Titanium Implants.
https://hdl.handle.net/20.500.12080/24524
Resumen:
Ca-P coatings on Ti implants have demonstrated good osseointegration capability due
to their similarity to bone mineral matter. Three databases (PubMed, Embase, andWeb of Science)
were searched electronically in February 2021 for preclinical studies in unmodified experimental
animals, with at least four weeks of follow-up, measuring bone-to-implant contact (BIC). Although
107 studies were found in the initial search, only eight experimental preclinical studies were included.
Adverse events were selected by two independent investigators. The risk of bias assessment of the
selected studies was evaluated using the Cochrane Collaboration Tool. Finally, a meta-analysis of the
results found no statistical significance between implants coated with Ca-P and implants with etched
conventional surfaces (difference of means, random effects: 5.40; 99% CI: ¿¿5.85, 16.65). With the
limitations of the present review, Ca-P-coated Ti surfaces have similar osseointegration performance
to conventional etched surfaces. Future well-designed studies with large samples are required to
confirm our findings.
Keywords: titanium dental implant; calcium-phosphate coating; osseointegration